Table 1

Lymphatic Filariasis

     • Caused by thread-like parasitic worms (Wuchereria bancrofti, Brugia malayi and Brugia timori) that damage the human lymphatic system – transmitted by mosquitoes (see 1)
     • One of the most disabling and disfiguring of diseases
     • 80+ endemic countries (Figure 1)
     • 1+ billion people are at risk of infection
     • 120 million people are infected. Of these...
          • 43 million people have swelling of the limbs and breasts (known as lymphoedema) and genitals (known as hydrocoele), and their more chronic state – known as elephantiasis – in which the skin becomes enormously thickened, and is rough, hard, and fissured
     • It is a disease of poverty – affecting the "poorest of the poor" – preventing those afflicted from living a normal working and social life (See 2)
     • Children acquire the disease early and are blighted for life

Molyneux Filaria Journal 2003 2:13   doi:10.1186/1475-2883-2-13