|
Impact of ivermectin distribution on four aspects of onchocerciasis infection and transmission. |
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| River Basin |
Intervention Strategy |
Impact of ivermectin treatment (Status in 2001) |
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|
|
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| PH problem eliminated (CMFL= 0) |
Prevalence of infection very low (< 10%) |
Transmission interrupted (Rx ongoing) |
Elimination (control ceased) |
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|
|
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| Ivermectin only: |
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| - River Gambia focus (A) |
6-Monthly ivm.1 since 1989 |
√ |
√ |
? |
– |
| - R. Corubal (B) (up to 1996) |
3-Monthly ivm. 1991–1996 |
√ |
√ |
? |
– |
| - R. Corubal (B) (from 1996 onwards) |
No ivm. since 1996 |
? |
Increasing prevalence |
Transmission ongoing |
– |
| - Rio Gêba (C) |
6-Monthly ivm. since 1989 and no treatment since 1996 |
√ |
√ |
? |
? |
| - Falémé (D), Bafing (E), Bakoye (F), Baoulé (G) |
Annual ivm. since 1989 |
√ |
√ |
? |
– |
| - Vina Valley (Cameroon) |
Annual ivm. since 1987 |
√ |
Prev. mf ≈ 20% in 1999 |
Transmission ongoing |
– |
| Ivermectin + vector control: |
|||||
| - Tienfala focus (H) |
Annual ivm. since 1987, and (ground) larv.2 since 1994 |
√ |
√ |
? |
– |
| - Bui Gorge focus (I) |
Annual ivm. since 1987 (3-monthly from 1994–1996), and larv. from 1975–1996 |
√ |
Prev. mf up to 55% in 1998 |
? |
– |
| - Titira and Kouporgou focus (J) |
Annual ivm. since 1988, and larv. since 1977 |
√ |
Prev. mf up to 50% in 1998 |
Transmission ongoing |
– |
| - Milo and Sankarani (K) |
Annual ivm. since 1989, and larv. since 1989 |
√ |
√ |
√ |
– |
| - Asubende focus (L) |
Annual ivm. since 1987, and larv. since 1990 |
√ |
√ |
Transmission ongoing |
– |
| - Dienkoa (M) |
Annual ivm. since 1988, and larv. since 1975 (with interruptions) |
√ |
√ |
√ |
– |
| Ivermectin treatment after vector control: |
|||||
| - Bougouriba (N) |
4-Monthly ivm. since 1996, and larv. from 1975–1990 |
√ |
√ |
Transmission ongoing |
– |
|
1ivm.: ivermectin treatment 2larv.: larviciding | |||||
Borsboom et al. Filaria Journal 2003 2:8 doi:10.1186/1475-2883-2-8 |
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