Table 2

Presenting symptoms and signs of SAE cases reported to have occurred following ivermectin mass treatment from 1989 to 2001*

Nature of Symptoms
Frequency of occurrence† (%)
Nature of Signs
Frequency of occurrence† (%)

Difficulty or inability to stand or walk
60 (29.0)
Altered Mental Status
106 (51.2)
Feverishness
54 (26.1)
Fever (documented)
51 (24.6)
Headache
52 (25.1)
Incontinence (urinary and/or fecal)
42 (20.3)
General myalgia or arthralgia
51 (24.6)
Dysarthria
26 (12.6)
Fatigue/Asthenia
40 (19.3)
Subconjunctival hemorrhage
26 (12.6)
Diarrhea
33 (15.9)
Rash and/or urticuria
23 (11.1)
Vertigo
31 (15.0)
Generalized edema
16 (7.7)
Dyspnea
22 (10.6)
Extremity edema
16 (7.7)
Pruritis
20 (9.7)
Facial edema
15 (7.3)
Nausea or vomiting
19 (9.1)
Hypotension (documented)
13 (6.3)

*cases reported as of August 31, 2002; †total of individual percentages is greater than 100 because most patients presented with multiple symptoms and signs.

Twum-Danso Filaria Journal 2003 2(Suppl 1):S3   doi:10.1186/1475-2883-2-S1-S3

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