The geographical distribution of lymphatic filariasis infection in Malawi

Bagrey MM Ngwira¹^,2, Phillimon Tambala³, A Maria Perez², Cameron Bowie² and David H Molyneux¹

¹Lymphatic Filariasis Support Centre, Liverpool School of Tropical Medicine, Pembroke Place, L3 5QA, UK

²Malawi College of Medicine, P/Bag 360, Blantyre3, Malawi

³Onchocerciasis Control Programme, PO Box 2273, Blantyre, Malawi

Filaria Journal 2007, 6:12doi:10.1186/1475-2883-6-12


Published:	29 November 2007

Abstract

Mapping distribution of lymphatic filariasis (LF) is a prerequisite for planning national elimination programmes. Results from a nation wide mapping survey for lymphatic filariasis (LF) in Malawi are presented. Thirty-five villages were sampled from 23 districts excluding three districts (Karonga, Chikwawa and Nsanje) that had already been mapped and Likoma, an Island, where access was not possible in the time frame of the survey. Antigenaemia prevalence [based on immunochromatographic card tests (ICT)] ranged from 0% to 35.9%. Villages from the western side of the country and distant from the lake tended to be of lower prevalence. The exception was a village in Mchinji district on the Malawi-Zambia border where a prevalence of 18.2% was found. In contrast villages from lake shore districts [Salima, Mangochi, Balaka and Ntcheu (Bwanje valley)] and Phalombe had prevalences of over 20%.

A national map is developed which incorporates data from surveys in Karonga, Chikwawa and Nsanje districts, carried out in 2000. There is a marked decline in prevalence with increasing altitude. Further analysis revealed a strong negative correlation (R²= 0.7 p < 0.001) between altitude and prevalence. These results suggest that the lake shore, Phalombe plain and the lower Shire valley will be priority areas for the Malawi LF elimination programme. Implications of these findings as regards implementing a national LF elimination programme in Malawi are discussed.